He wrote for the Back to the Future comic book series for Harvey Comics.
Dwayne McDuffie was a co-founder of Milestone Media which was geared towards comic books providing focus on minority characters. It's earliest titles which McDuffie wrote included Hardware, Icon, Blood Syndicate and Static.
He also went on to write the 2000 cartoon series based on Static which was retitled as Static Shock.
- Avengers Annual #19 story "Media Watch" (1990)
- Avengers Spotlight #26-29 (1989-1990)
- Damage Control Volume 2 #1-4 (1989)
- Double Dragon #1-4 (1991)
- Fantastic Four #542-553 (2007-2008)
- Iron Man #251-252 (1989-1990)
- What If? Volume 2 #18 (1990)
- JLA Showcase 80 Page Giant #1 story "Communications Error" (2000)
- Justice League: Crisis on Two Earths (Writer)(2010)
- Josh Keaton provided the voice of both The Flash and Aquaman.
- All-Star Superman (Writer)(2011)
- Cathy Cavadini provided the voice of Catherine Grant.
- Justice League: Doom (Writer)(2012)